There is not such a way to redirect the internal requests between different regions.
Scenario Highly available ADFS deployment as showed below
• 2 internal ADFS servers each one located on a different region (1st in Azure North Central US and the 2nd in Azure West Europe).
• 2 WAP servers with NSG each one located on a different region (1st in Azure North Central US and the 2nd in Azure West Europe).
• 1 external traffic manager located in the Azure East US.

The missing item to this deployment is the internal traffic manager where it is not supported in Azure. So the question that occurs is...how are we redirect the internal traffic to the ADFS server in West EU and the same for the ADFS server located in the NCUS? The new 2016 DNS functionalities do not fit into this deployment since the failover capabilities are totally missing.